June 19, 2013, EXTON, PA – Fibrocell Science, Inc. (NYSE MKT:FCSC), an autologous cell therapy company focused on the development of innovative products for aesthetic, medical and scientific applications, announced today that it will be included in the Russell Global, the Russell 3000®, and the Russell Microcap Indexes when Russell Investments reconstitutes its comprehensive set of U.S. and global equity indexes on June 28, according to a preliminary list of additions posted June 14 on www.russell.com/indexes.

David Pernock, Chief Executive Officer and Chairman of Fibrocell Science, said, “Inclusion in the Russell indexes is a major milestone for the Company and reflects our successful listing on the NYSE MKT exchange in May. It also reflects the continued broadening of our autologous fibroblast technology, LAVIV® (azficel-T), in aesthetics and to address unmet medical needs, such as restrictive burn scarring, vocal cord scarring, and recessive dystrophic epidermolysis bullosa (RDEB), a rare collagen deficiency that typically presents at birth.” LAVIV is the first and only autologous cellular product approved by the FDA to improve the appearance of moderate to severe nasolabial folds (smile lines) in adults.

Membership in the Russell indexes, which remains in place for one year, means automatic inclusion in the appropriate market capitalization weighed indexes as well as the appropriate growth and value style indexes. Russell determines membership for its equity indexes primarily by objective, market-capitalization rankings and style attributes. Russell indexes are widely used by investment managers and institutional investors for index funds and as benchmarks for both passive and active investment strategies. Approximately $4.1 trillion in assets currently are benchmarked to these indexes. Russell calculates more than 700,000 benchmarks daily covering approximately 98 percent of the investable market globally, 80 countries and more than 10,000 securities.

Russell launched the Russell Global Index in 2007, leveraging the popular methodology from its U.S. indexes, which originated from Russell’s multi-manager investment business in the early 1980s when the company saw the need for a more objective, market-driven set of benchmarks in order to evaluate outside investment managers. The annual reconstitution of Russell’s U.S. indexes captures the 4,000 largest U.S. stocks as of the end of May, ranking them by total market capitalization to create the Russell 3000® Index and the Russell Microcap Index.

Total returns data for the Russell Global Index and other Russell Indexes is available at http://www.russell.com/indexes/data/Global_Equity/Russell_Global_returns.asp.

About Russell Investments

Russell Investments (Russell) is a global asset manager and one of only a few firms that offers actively managed multi-asset portfolios and services that include advice, investments and implementation. Russell stands with institutional investors, financial advisors and individuals working with their advisors—using the firm’s core capabilities that extend across capital market insights, manager research, portfolio construction, portfolio implementation and indexes to help each achieve their desired investment outcomes.

Russell has more than $173 billion in assets under management (as of 3/31/2013) and works with over 2,500 institutional clients, independent distribution partners and individual investors globally. As a consultant to some of the largest pools of capital in the world, Russell has $2.6 trillion in assets under advisement (as of 12/31/2012). It has four decades of experience researching and selecting investment managers and meets annually with more than 2,200 managers around the world. Russell traded more than $1.4 trillion in 2012 through its implementation services business.

About Fibrocell Science, Inc.

Fibrocell Science, Inc. (NYSE MKT: FCSC) is an autologous cell therapy company focused on the development of innovative products for aesthetic, medical and scientific applications. Fibrocell Science is committed to advancing the scientific, medical and commercial potential of autologous skin and tissue, as well as its innovative cellular processing technology and manufacturing excellence. For additional information, please visit www.fibrocellscience.com.

About LAVIV® (azficel-T)

LAVIV is an autologous cellular product indicated for improvement of the appearance of moderate to severe nasolabial fold wrinkles in adults. The safety and efficacy of LAVIV for areas other than the nasolabial folds have not been established. The efficacy of LAVIV beyond six months has not been established.

Important Safety Information about LAVIV® (azficel-T)

LAVIV (azficel-T) is an autologous cellular product for intradermal injection only. LAVIV is contraindicated for allogeneic use, in patients with allergy to gentamicin, amphotericin, dimethyl sulfoxide (DMSO) or material of bovine origin and in patients with active infection in the facial area. The following reactions have been reported following treatment with LAVIV: hypersensitivity reactions, bleeding and bruising at the treatment site, vasculitis, herpes labialis, basal cell cancer; keloid and hypertrophic scarring may occur following post-auricular skin biopsies or LAVIV injections. Additional warnings and precautions to be considered include the use of LAVIV in patients with genetic disorders or formation of normal collagen matrices and in immunosuppressed patients, or those patients undergoing chemotherapy for malignancies or receive immunomodulatory therapies for autoimmune diseases.

The most common adverse reactions, occurring in ≥1% of patients who receive LAVIV, were injection-site redness, bruising, swelling, pain, hemorrhage, edema, nodules, papules, irritation, dermatitis and pruritus.

For more information about LAVIV, please see the accompanying full Prescribing Information or visit www.mylaviv.com.

Forward-Looking Statements

All statements in this press release that are not based on historical fact are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of

1995 and the provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. While management has based any forward-looking statements contained herein on its current expectations, the information on which such expectations were based may change. These forward-looking statements rely on a number of assumptions concerning future events and are subject to a number of risks, uncertainties, and other factors, many of which are outside of the Company’s control, that could cause actual results to materially differ from such statements. Such risks, uncertainties, and other factors include, but are not necessarily limited to, those set forth under Item 1A “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2012, as updated in “Item 1A. Risk Factors” in the Company’s Quarterly Reports on Form 10-Q filed since the annual report. The Company operates in a highly competitive and rapidly changing environment, thus new or unforeseen risks may arise. Accordingly, investors should not place any reliance on forward-looking statements as a prediction of actual results. The Company disclaims any intention to, and undertakes no obligation to, update or revise any forward-looking statements. Readers are also urged to carefully review and consider the other various disclosures in the Company’s public filings with the SEC.

Contacts

Media:
Marina Maher Communications, LLC
Heather Adamson
212-485-6806
hadamson@mahercomm.com

or

Investor Relations:
The Ruth Group
Stephanie Carrington, 646-536-7017
scarrington@theruthgroup.com

“We are pleased that the New York Stock Exchange has given Fibrocell the honor of ringing the Closing Bell. This occasion marks the successful listing of our stock on the NYSE MKT,” Pernock said. “We are focused on expanding the applications of our FDA-approved product, LAVIV® (azficel-T), to areas of significant unmet medical needs such as restrictive burn scarring, vocal cord scarring and acne scarring.”

“In addition, we have entered into an exclusive channel collaboration (ECC) with Intrexon Corporation to explore the use of genetically-modified autologous fibroblast cells for Recessive Dystrophic Epidermolysis Bullosa, the most severe form of a debilitating genetic blistering disorder,” Pernock said.

The Closing Bell is televised live on CNBC and also airs online at https://nyse.nyx.com/the-bell/todays-bells-live at 4 p.m. ET. Web viewers may need to refresh their browsers ahead of 4 p.m. to start the live feed.

Photographs from the Closing Bell ceremony and a recording of the event, provided by NYSE, will be available on www.fibrocellscience.com on Wednesday, June 5, 2013.

About Fibrocell Science, Inc.

Fibrocell Science, Inc. (FCSC) is an autologous cell therapy company focused on the development of innovative products for aesthetic, medical and scientific applications. Fibrocell Science is committed to advancing the scientific, medical and commercial potential of autologous skin and tissue, as well as its innovative cellular processing technology and manufacturing excellence. For additional information, please visit www.fibrocellscience.com.

About LAVIV® (azficel-T)

LAVIV is the first and only autologous fibroblast cellular product approved by the FDA to improve the appearance of moderate to severe nasolabial fold (smile line) wrinkles in adults. It has been evaluated in more than 1,000 patients in clinical studies, including two pivotal Phase III trials. The safety and efficacy of LAVIV for areas other than the nasolabial folds have not been established. The efficacy of LAVIV beyond six months has not been established.

Important Safety Information about LAVIV® (azficel-T)

LAVIV (azficel-T) is an autologous cellular product for intradermal injection only. LAVIV is contraindicated for allogeneic use, in patients with allergy to gentamicin, amphotericin, dimethyl sulfoxide (DMSO) or material of bovine origin and in patients with active infection in the facial area. The following reactions have been reported following treatment with LAVIV: hypersensitivity reactions, bleeding and bruising at the treatment site, vasculitis, herpes labialis, basal cell cancer; keloid and hypertrophic scarring may occur following post-auricular skin biopsies or LAVIV injections. Additional warnings and precautions to be considered include the use of LAVIV in patients with genetic disorders or formation of normal collagen matrices and in immunosuppressed patients, or those patients undergoing chemotherapy for malignancies or receive immunomodulatory therapies for autoimmune diseases.

The most common adverse reactions, occurring in ≥1% of patients who receive LAVIV, were injection-site redness, bruising, swelling, pain, hemorrhage, edema, nodules, papules, irritation, dermatitis and pruritus.

For more information about LAVIV, please see the accompanying full Prescribing Information or visit www.mylaviv.com.

Forward-Looking Statements

All statements in this press release that are not based on historical fact are “forward-

looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and the provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements include, without limitation, the Company’s ability to expand the indications of azficel-T into significant medical applications for which there are no currently approved medical options. While management has based any forward-looking statements contained herein on its current expectations, the information on which such expectations were based may change. These forward-looking statements rely on a number of assumptions concerning future events and are

subject to a number of risks, uncertainties, and other factors, many of which are outside of the Company’s control, that could cause actual results to materially differ from such statements. Such risks, uncertainties, and other factors include, but are not necessarily limited to, those set forth under Item 1A “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2012, as updated in “Item 1A. Risk Factors” in the Company’s Quarterly Reports on Form 10-Q filed since the annual report. The Company operates in a highly competitive and rapidly changing environment, thus new or unforeseen risks may arise. Accordingly, investors should not place any reliance on forward-looking statements as a prediction of actual results. The Company disclaims any intention to, and undertakes no obligation to, update or revise any forward-looking statements. Readers are also urged to carefully review and consider the other various disclosures in the Company’s public filings with the SEC.

“The NYSE MKT listing is a significant corporate milestone for Fibrocell Science. The NYSE listing should enable us to increase the trading liquidity of our stock, broaden our shareholder base, and raise our profile in the investment community,” said David Pernock, Chairman and Chief Executive Officer, Fibrocell Science. “We also believe that listing on the NYSE increases the awareness of our FDA-approved product LAVIV® (azficel-T), as well as our pipeline for the treatment of restrictive burn, vocal cord and acne scarring, and state-of-the-art medicines in development for rare genetic skin diseases,” added Mr. Pernock.

“We welcome Fibrocell to the NYSE MKT family of listed companies,” said Scott Cutler, Executive Vice President, Global Listings at NYSE Euronext. “Fibrocell will be joining other growth oriented companies in the U.S. taking advantage of the NYSE’s advanced and innovative market model to offer a premier value for listing and trading their stocks.”

About Fibrocell Science, Inc.

Fibrocell Science, Inc. (FCSCD) is an autologous cell therapy company focused on the development of innovative products for aesthetic, medical and scientific applications. Fibrocell Science is committed to advancing the scientific, medical and commercial potential of autologous skin and tissue, as well as its innovative cellular processing technology and manufacturing excellence. For additional information, please visit www.fibrocellscience.com.

About LAVIV® (azficel-T)

LAVIV is an autologous cellular product indicated for improvement of the appearance of moderate to severe nasolabial fold wrinkles in adults. The safety and efficacy of LAVIV for areas other than the nasolabial folds have not been established. The efficacy of LAVIV beyond six months has not been established.

Important Safety Information About LAVIV® (azficel-T)

LAVIV (azficel-T) is an autologous cellular product for intradermal injection only. LAVIV is contraindicated for allogeneic use, in patients with allergy to gentamicin, amphotericin, dimethyl sulfoxide (DMSO) or material of bovine origin and in patients with active infection in the facial area. The following reactions have been reported following treatment with LAVIV: hypersensitivity reactions, bleeding and bruising at the treatment site, vasculitis, herpes labialis, basal cell cancer; keloid and hypertrophic scarring may occur following post-auricular skin biopsies or LAVIV injections. Additional warnings and precautions to be considered include the use of LAVIV in patients with genetic disorders or formation of normal collagen matrices and in immunosuppressed patients, or those patients undergoing chemotherapy for malignancies or receive immunomodulatory therapies for autoimmune diseases.

The most common adverse reactions, occurring in ≥1% of patients who receive LAVIV, were injection-site redness, bruising, swelling, pain, hemorrhage, edema, nodules, papules, irritation, dermatitis and pruritus.

For more information about LAVIV, please see the accompanying full Prescribing Information or visit www.mylaviv.com.

Forward-Looking Statements

All statements in this press release that are not based on historical fact are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and the provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements include, without limitation, the timing of the commencement of trading on the NYSE MKT. While management has based any forward-looking statements contained herein on its current expectations, the information on which such expectations were based may change. These forward-looking statements rely on a number of assumptions concerning future events and are subject to a number of risks, uncertainties, and other factors, many of which are outside of the Company’s control, that could cause actual results to materially differ from such statements. Such risks, uncertainties, and other factors include, but are not necessarily limited to, those set forth under Item 1A “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2012, as updated in “Item 1A. Risk Factors” in the Company’s Quarterly Reports on Form 10-Q filed since the annual report. The Company operates in a highly competitive and rapidly changing environment, thus new or unforeseen risks may arise. Accordingly, investors should not place any reliance on forward-looking statements as a prediction of actual results. The Company disclaims any intention to, and undertakes no obligation to, update or revise any forward-looking statements. Readers are also urged to carefully review and consider the other various disclosures in the Company’s public filings with the SEC.
Contacts

Media:
Marina Maher Communications, LLC
Heather Adamson
212-485-6806
hadamson@mahercomm.com

or

Investor Relations:
The Ruth Group
Stephanie Carrington, 646-536-7017
scarrington@theruthgroup.com

May 02, 2013, EXTON, PA – Fibrocell Science, Inc. (OTC: FCSCD) announced today the initiation of a Phase II trial for azficel-T, an autologous fibroblast cellular product, for the treatment of restrictive burn scars (RBS).

The Phase II double-blind, randomized, placebo-controlled study will enroll 21 participants with burn scars that restrict range of motion of jointed areas such as elbows, shoulders and fingers. The study is led by Daniel D. Lozano, M.D., M.B.A., Chief of Burn Surgery at Lehigh Valley Health Network’s Burn Center in Allentown, Pa. Lehigh Valley Burn Center is one of 63 burn centers in the U.S. verified by the American Burn Association and American College of Surgeons for providing high quality care to patients from time of their injury through rehabilitation, and it is Pennsylvania’s largest and busiest burn center.

Restrictive burn scars represent an unmet medical need with no existing FDA-approved drugs. Approximately 45,000 burn victims are hospitalized every year in the U.S. This estimate does not include military personnel and does not take into account the large pool of victims with existing burns⁽¹⁾. About half of hospitalized burn patients will develop some restrictive scarring⁽²⁾.

Measurement scales will assess range of motion (ROM), brief pain index and scar appearance. Primary efficacy and safety endpoints will be evaluated six months after patients are administered azficel-T or placebo.

“Restrictive burn scars over joints can lead to a reduction in range of motion and may cause significant pain and discomfort for the patient. This category of scarring can adversely impact the patient’s quality of life,” said Lozano. “A treatment using an individual’s own fibroblast cells provides the potential for a truly biologic, non-surgical approach to treat restrictive scars.”

As one of only three cell-based products approved by the FDA, azficel-T (LAVIV®) is the first and only approved for aesthetic use that utilizes a patient’s own cells. This same technology is being evaluated in this Phase II trial for treating restrictive burn scars. Current standard of care for RBS is surgery or lasers.

“We believe leveraging the technology of LAVIV will help us address high-value, unmet medical needs,” said David Pernock, Chairman and CEO of Fibrocell Science, Inc. “In addition to the aesthetic benefits of autologous fibroblasts, we are encouraged by their potential for the treatment of restrictive burn scarring. Patients have experienced the functional benefits of fibroblasts in individual case studies and we hope to confirm those benefits in the Phase II trial.”

Fibroblast cells make collagen, a protein that gives skin its strength and elasticity. LAVIV is the first and only autologous fibroblast cellular product approved by the FDA to improve the appearance of moderate to severe nasolabial fold (smile line) wrinkles in adults. It has been evaluated in more than 1,000 patients in clinical studies, including two pivotal Phase III trials.

Separately, on Monday, April 29, 2013 Fibrocell announced a reverse split of its common shares of 25 shares to one. The shares started trading with the revised split on Tuesday, April 30, 2013. The Company said it has been cleared to submit a listing application to NYSE MKT.

About Fibrocell Science, Inc.

Fibrocell Science, Inc. (FCSCD) is an autologous cell therapy company focused on the development of innovative products for aesthetic, medical and scientific applications. Fibrocell Science is committed to advancing the scientific, medical and commercial potential of autologous skin and tissue, as well as its innovative cellular processing technology and manufacturing excellence. For additional information, please visit www.fibrocellscience.com.

About LAVIV® (azficel-T)

LAVIV is an autologous cellular product indicated for improvement of the appearance of moderate to severe nasolabial fold wrinkles in adults. The safety and efficacy of LAVIV for areas other than the nasolabial folds have not been established. The efficacy of LAVIV beyond six months has not been established.

Important Safety Information about LAVIV® (azficel-T)

LAVIV (azficel-T) is an autologous cellular product for intradermal injection only. LAVIV is contraindicated for allogeneic use, in patients with allergy to gentamicin, amphotericin, dimethyl sulfoxide (DMSO) or material of bovine origin and in patients with active infection in the facial area. The following reactions have been reported following treatment with LAVIV: hypersensitivity reactions, bleeding and bruising at the treatment site, vasculitis, herpes labialis, basal cell cancer; keloid and hypertrophic scarring may occur following post-auricular skin biopsies or LAVIV injections. Additional warnings and precautions to be considered include the use of LAVIV in patients with genetic disorders or formation of normal collagen matrices and in immunosuppressed patients, or those patients undergoing chemotherapy for malignancies or receive immunomodulatory therapies for autoimmune diseases.

The most common adverse reactions, occurring in ≥1% of patients who receive LAVIV, were injection-site redness, bruising, swelling, pain, hemorrhage, edema, nodules, papules, irritation, dermatitis and pruritus.

For more information about LAVIV, please see the accompanying full Prescribing Information or visit www.mylaviv.com.

Forward-Looking Statements

All statements in this press release that are not based on historical fact are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of

1995 and the provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. While management has based any forward-looking statements contained herein on its current expectations, the information on which such expectations were based may change. These forward-looking statements rely on a number of assumptions concerning future events and are subject to a number of risks, uncertainties, and other factors, many of which are outside of the Company’s control, that could cause actual results to materially differ from such statements. Such risks, uncertainties, and other factors include, but are not necessarily limited to, those set forth under Item 1A “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2012, as updated in “Item 1A. Risk Factors” in the Company’s Quarterly Reports on Form 10-Q filed since the annual report. The Company operates in a highly competitive and rapidly changing environment, thus new or unforeseen risks may arise. Accordingly, investors should not place any reliance on forward-looking statements as a prediction of actual results. The Company disclaims any intention to, and undertakes no obligation to, update or revise any forward-looking statements. Readers are also urged to carefully review and consider the other various disclosures in the Company’s public filings with the SEC.

⁽¹⁾ American Burn Association. www.ameriburn.org; Goodis. J and E.d. Schraga. Burns, thermal. eMedicine Journal.

⁽²⁾ Personal communications with several expert burn clinicians.

Contacts

Media:
Marina Maher Communications, LLC
Heather Adamson
212-485-6806
hadamson@mahercomm.com

or

Investor Relations:
The Ruth Group
Stephanie Carrington
646-536-7017 (direct)
scarrington@theruthgroup.com

April 29, 2013, EXTON, PA – Fibrocell Science, Inc. (OTC BB: FCSC) announced today that it will implement a one-for-twenty-five reverse stock split of its common shares effective at the opening of business on April 30, 2013. The Company has also been cleared to submit a listing application to the NYSE MKT. The Company’s ability to become listed on the NYSE MKT is subject to, among other items, maintaining a minimum market price for its common stock for a sufficient period of time as determined by the exchange.

“We believe the reverse stock split is the last step to obtaining a listing on a national securities exchange, and an uplisting would increase the attractiveness of Fibrocell’s common stock among institutional and retail investors focused on national exchange listed securities,” said David Pernock, CEO and Chairman of the Board, Fibrocell Science.

The reverse stock split was approved by shareholders on September 13, 2012 at the Company’s 2012 annual meeting. On April 30, 2013, the Company’s shares will trade in the OTC BB market under the symbol “FCSCD,” with a “D” added for 20 trading days to signify that the reverse stock split has occurred. A new CUSIP number has been assigned to the Company’s common stock as a result of the reverse split. The reverse split reduced the number of shares of outstanding common stock to approximately 26.2 million shares. Informational letters will be sent to all shareholders of record by the Company’s transfer agent, American Stock Transfer & Trust Company. Additional information about the reverse stock split can be found in the Company’s Form 8-K filed today with the Securities and Exchange Commission.

About Fibrocell Science, Inc.

Fibrocell Science, Inc. (FCSC) is an autologous cell therapy company focused on the development of innovative products for aesthetic, medical and scientific applications. Fibrocell Science is committed to advancing the scientific, medical and commercial potential of autologous skin and tissue, as well as its innovative cellular processing technology and manufacturing excellence. For additional information, please visit www.fibrocellscience.com.

Forward-Looking Statements

All statements in this press release that are not based on historical fact are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and the provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements include, without limitation, the company’s ability to become listed on a national securities exchange. While management has based any forward-looking statements contained herein on its current expectations, the information on which such expectations were based may change. These forward-looking statements rely on a number of assumptions concerning future events and are subject to a number of risks, uncertainties, and other factors, many of which are outside of the Company’s control, that could cause actual results to materially differ from such statements. Such risks, uncertainties, and other factors include, but are not necessarily limited to, those set forth under Item 1A “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2012, as updated in “Item 1A. Risk Factors” in the Company’s Quarterly Reports on Form 10-Q filed since the annual report. The Company operates in a highly competitive and rapidly changing environment, thus new or unforeseen risks may arise. Accordingly, investors should not place any reliance on forward-looking statements as a prediction of actual results. The Company disclaims any intention to, and undertakes no obligation to, update or revise any forward-looking statements. Readers are also urged to carefully review and consider the other various disclosures in the Company’s public filings with the SEC.

Contacts

April 26, 2013, EXTON, PA – Fibrocell Science, Inc. (OTC: FCSC) today announced that LAVIV® (azficel-T) was recognized as the Silver Winner in aesthetics of the science/medical category at the 2013 Edison Awards Ceremony and Gala in Chicago. LAVIV is the first and only autologous cellular product approved by the FDA to improve the appearance of moderate to severe nasolabial folds (smile lines) in adults. The distinguished Edison Awards symbolize the persistence and excellence personified by Thomas Alva Edison, inspiring creative minds to remain in the forefront of innovation, creativity and ingenuity in the global economy.

“We are honored that the Edison Awards have presented LAVIV with this prestigious accolade for innovation,” said David Pernock, CEO and Chairman of the Board, Fibrocell Science, Inc. “This award highlights the innovative technology behind LAVIV, which isolates, purifies and multiplies a patient’s own collagen-producing fibroblast cells. We look forward to advancing our autologous fibroblast technology to new indications that address areas with high value, unmet medical needs, such as restrictive burn scars, vocal cord scars, and recessive dystrophic epidermolysis bullosa (RDEB), a rare genetic collagen deficiency.”

Hundreds of nominees for the Edison Awards were judged by more than 3,000 senior business executives and academics from across the nation whose votes acknowledge Edison Award Finalists’ success in meeting the award criteria of Concept, Value, Delivery and Impact. A total of 130 Edison Awards across 15 different categories were presented on April 25, 2013.

About Edison Awards

The Edison Awards is a program conducted by Edison Universe, a 501(c)(3) charitable organization dedicated to fostering future innovators. While the Awards honor invention, recognize achievement and celebrate success, Edison Universe is focused on fostering innovation. The 2013 Edison Awards are sponsored by Nielsen, Discovery Communications, Science Channel, and USA Today. For more information about the Edison Awards, Edison Universe and a list of past winners, visit www.edisonawards.com.

About Fibrocell Science, Inc.

Fibrocell Science, Inc. (FCSC) is an autologous cell therapy company focused on the development of innovative products for aesthetic, medical and scientific applications. Fibrocell Science is committed to advancing the scientific, medical and commercial potential of autologous skin and tissue, as well as its innovative cellular processing technology and manufacturing excellence. For additional information, please visit www.fibrocellscience.com.

About LAVIV® (azficel-T)

LAVIV is an autologous cellular product indicated for improvement of the appearance of moderate to severe nasolabial fold wrinkles in adults. The safety and efficacy of LAVIV for areas other than the nasolabial folds have not been established. The efficacy of LAVIV beyond six months has not been established.

Important Safety Information about LAVIV® (azficel-T)

LAVIV (azficel-T) is an autologous cellular product for intradermal injection only. LAVIV is contraindicated for allogeneic use, in patients with allergy to gentamicin, amphotericin, dimethyl sulfoxide (DMSO) or material of bovine origin and in patients with active infection in the facial area. The following reactions have been reported following treatment with LAVIV: hypersensitivity reactions, bleeding and bruising at the treatment site, vasculitis, herpes labialis, basal cell cancer; keloid and hypertrophic scarring may occur following post-auricular skin biopsies or LAVIV injections. Additional warnings and precautions to be considered include the use of LAVIV in patients with genetic disorders or formation of normal collagen matrices and in immunosuppressed patients, or those patients undergoing chemotherapy for malignancies or receive immunomodulatory therapies for autoimmune diseases.

The most common adverse reactions, occurring in ≥1% of patients who receive LAVIV, were injection-site redness, bruising, swelling, pain, hemorrhage, edema, nodules, papules, irritation, dermatitis and pruritus.

For more information about LAVIV, please see the accompanying full Prescribing Information or visit www.mylaviv.com.

Forward-Looking Statements

All statements in this press release that are not based on historical fact are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and the provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. While management has based any forward-looking statements contained herein on its current expectations, the information on which such expectations were based may change. These forward-looking statements rely on a number of assumptions concerning future events and are subject to a number of risks, uncertainties, and other factors, many of which are outside of the Company’s control, that could cause actual results to materially differ from such statements. Such risks, uncertainties, and other factors include, but are not necessarily limited to, those set forth under Item 1A “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2012, as updated in “Item 1A. Risk Factors” in the Company’s Quarterly Reports on Form 10-Q filed since the annual report. The Company operates in a highly competitive and rapidly changing environment, thus new or unforeseen risks may arise. Accordingly, investors should not place any reliance on forward-looking statements as a prediction of actual results. The Company disclaims any intention to, and undertakes no obligation to, update or revise any forward-looking statements. Readers are also urged to carefully review and consider the other various disclosures in the Company’s public filings with the SEC.

April 24, 2013, EXTON, PA – Fibrocell Science, Inc. (OTC: FCSC) today announced revised pricing for LAVIV® (azficel-T) reflecting the growing value of the product to both physicians and patients. LAVIV is the first and only FDA-approved product that uses the patient’s own collagen-producing fibroblast cells to improve the appearance of moderate to severe nasolabial fold wrinkles (smile lines) in adults. The product continues to gain acceptance in the premium aesthetic market, and the new pricing better reflects the value of this unique product. LAVIV has received recognition in national beauty and fashion magazines, including receipt of the prestigious Allure magazine ‘Breakthrough Award’ in 2011. The product has also been recognized for its innovation, including in the 12^th Annual Wall Street Journal Technology Innovation Awards program.

An introductory price for LAVIV was originally set in order to stimulate usage and generate clinical experience with the product. With LAVIV now in the market for more than a year, the company has established a new suggested retail price of $19,900 effective May 1, 2013 for a patient’s full course of treatment—three treatment sessions spaced at intervals of three to six weeks. The commercial introduction of LAVIV has been driven primarily by positive patient and physician experience.

LAVIV launched in January 2012 and is marketed to leading aesthetic physicians in major U.S. markets as an important addition and complement to existing aesthetic offerings. LAVIV addresses a patient’s desire for a more natural approach. With age, fibroblast cells, which produce collagen, diminish, resulting in the dermis layer growing thinner, less resilient and more prone to wrinkling. Unlike any other product on the market, LAVIV contains a patient’s own fibroblast cells which are harvested from behind the ear and then re-injected into smile lines.

“We believe the use of the patient’s own fibroblast cells helps enable an optimal aesthetic result. These sentiments are echoed by our customers, who are leaders in the aesthetic field, and who see firsthand the benefits LAVIV offers their patients,” said David Pernock, Chief Executive Officer and Chairman of the Board, Fibrocell Science. “As a pioneer in personalized medicine, it is our pleasure to offer a premium aesthetic product to our customers and their patients. We believe this is just the beginning of the significant role our autologous fibroblast technology will play in addressing patient needs.”

Fibrocell is leveraging its technology and expertise to expand into other medical applications in which fibroblasts have the potential to treat unmet medical needs, including restrictive burn scars, vocal cord scars, acne scars and rare genetic collagen deficiencies such as Recessive Dystrophic Epidermolysis Bullosa (RDEB). The company plans to initiate Phase II trials for the treatment of restrictive burn scars and vocal cord scars later this year. The company is also in discussions with the FDA regarding the next phase in its program to explore the treatment of moderate to severe acne scars. There are currently no FDA-approved products to treat these indications.

Recently the company entered an exclusive channel collaboration with Intrexon Corporation. The collaboration leverages Fibrocell’s fibroblast expertise and Intrexon’s synthetic biology expertise. One of the collaboration’s goals is to treat the rare genetic condition, Recessive Dystrophic Epidermolysis Bullosa, using a patient’s own fibroblasts to produce functional collagen VII. “RDEB is a very serious genetic disorder,” said Professor Jouni Uitto, Chair, Department of Dermatology & Cutaneous Biology at Thomas Jefferson University, Philadelphia, PA. “It is characterized by the presence of extremely fragile skin and recurrent blister formation, resulting from minor mechanical friction or trauma and often leading to early demise of the affected individuals. An estimated 1 out of every 20,000 births are affected with some type of EB. The disorder occurs in every racial and ethnic group throughout the world and affects both sexes equally.”

About Fibrocell Science, Inc.

Fibrocell Science, Inc. (FCSC) is an autologous cell therapy company focused on the development of innovative products for aesthetic, medical and scientific applications. Fibrocell Science is committed to advancing the scientific, medical and commercial potential of autologous skin and tissue, as well as its innovative cellular processing technology and manufacturing excellence. For additional information, please visit www.fibrocellscience.com.

About LAVIV® (azficel-T)

LAVIV is an autologous cellular product indicated for improvement of the appearance of moderate to severe nasolabial fold wrinkles in adults. The safety and efficacy of LAVIV for areas other than the nasolabial folds have not been established. The efficacy of LAVIV beyond six months has not been established.

Important Safety Information About LAVIV® (azficel-T)

LAVIV (azficel-T) is an autologous cellular product for intradermal injection only. LAVIV is contraindicated for allogeneic use, in patients with allergy to gentamicin, amphotericin, dimethyl sulfoxide (DMSO) or material of bovine origin and in patients with active infection in the facial area. The following reactions have been reported following treatment with LAVIV: hypersensitivity reactions, bleeding and bruising at the treatment site, vasculitis, herpes labialis, basal cell cancer; keloid and hypertrophic scarring may occur following post-auricular skin biopsies or LAVIV injections. Additional warnings and precautions to be considered include the use of LAVIV in patients with genetic disorders or formation of normal collagen matrices and in immunosuppressed patients, or those patients undergoing chemotherapy for malignancies or receive immunomodulatory therapies for autoimmune diseases.

The most common adverse reactions, occurring in ≥1% of patients who receive LAVIV, were injection-site redness, bruising, swelling, pain, hemorrhage, edema, nodules, papules, irritation, dermatitis and pruritus.

For more information about LAVIV, please see the accompanying full Prescribing Information or visit www.mylaviv.com.

Forward-Looking Statements

All statements in this press release that are not based on historical fact are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and the provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. While management has based any forward-looking statements contained herein on its current expectations, the information on which such expectations were based may change. These forward-looking statements rely on a number of assumptions concerning future events and are subject to a number of risks, uncertainties, and other factors, many of which are outside of the Company’s control, that could cause actual results to materially differ from such statements. Such risks, uncertainties, and other factors include, but are not necessarily limited to, those set forth under Item 1A “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2012, as updated in “Item 1A. Risk Factors” in the Company’s Quarterly Reports on Form 10-Q filed since the annual report. The Company operates in a highly competitive and rapidly changing environment, thus new or unforeseen risks may arise. Accordingly, investors should not place any reliance on forward-looking statements as a prediction of actual results. The Company disclaims any intention to, and undertakes no obligation to, update or revise any forward-looking statements. Readers are also urged to carefully review and consider the other various disclosures in the Company’s public filings with the SEC.

Study Reporting Long-Term Improvement with No Lasting Adverse Effects Accepted for Publication in Dermatologic Surgery

April 15, 2013, EXTON, PA – Fibrocell Science, Inc. (OTC: FCSC) today announced that its Phase 2 study to evaluate the safety and efficacy of azficel-T (LAVIV®) for the treatment of patients with moderate-to-severe acne scars has been accepted for publication in Dermatologic Surgery, the peer-reviewed journal of the American Society for Dermatologic Surgery. The findings demonstrated that azficel-T treatment was associated with clinically meaningful improvement in acne scar appearance and was judged safe and superior to control treatment. The Early View (Online Version of Record) of the article is available at http://onlinelibrary.wiley.com/doi/10.1111/dsu.12204/pdf.

According to the American Academy of Dermatology, an estimated 20 million Americans have acne badly enough to cause scarring—a condition caused by damage that occurs under the skin’s surface. Scars can appear as ice pick-like holes, or crater-like fixed or distensible depressions. The skin typically loses its underlying support and develops an uneven, poor texture.

David Pernock, CEO and Chairman of the Board, Fibrocell Science, stated, “We are pleased to report that the outcomes of this study correlate to clinically meaningful improvements in acne scar appearance. The study finds Fibrocell’s autologous fibroblast treatment safe and superior to the placebo for the improvement in scar appearance.”

Fibroblasts are cells that recreate collagen and other extracellular matrix proteins, which form the infrastructure of human tissue. Autologous fibroblasts are extracted from behind a patient’s ear, harvested, and then re-injected at the site of the patient’s acne scars.

“Of all skin changes possible after acne eruptions, scarring leaves the most potentially permanent, cosmetically and psychologically devastating effects,” said lead investigator Gilly S. Munavalli, MD, MHS, FACMS, Dermatology, Laser & Vein Specialists of the Carolinas, Charlotte, NC. “In this study, both patients and physicians reported significant improvements from the autologous fibroblast injections, so the research is very promising.”

“Using a patient’s own collagen-producing fibroblast cells to treat these wide, shallow acne scars makes so much sense,” said Robert Weiss, MD, Maryland Laser, Skin and Vein Institute, Baltimore, MD, who was also an investigator in the multi-site, randomized, double-blind placebo-controlled study. “LAVIV has an excellent safety profile and there is minimal downtime, as well as a reduced risk of infection or adverse drug reactions.”

About Fibrocell Science, Inc.

Fibrocell Science, Inc. (FCSC) is an autologous cellular therapeutic company focused on the development of innovative products for aesthetic, medical and scientific applications. Fibrocell Science is committed to advancing the scientific, medical and commercial potential of autologous skin and tissue, as well as its innovative cellular processing technology and manufacturing excellence. For additional information, please visit www.fibrocellscience.com.

About LAVIV® (azficel-T) from Fibrocell Science

LAVIV is an autologous cellular product indicated for improvement of the appearance of moderate to severe nasolabial fold wrinkles in adults. The safety and efficacy of LAVIV for areas other than the nasolabial folds have not been established. The efficacy of LAVIV beyond six months has not been established.

Important Safety Information About LAVIV® (azficel-T)

LAVIV is made especially for you from your own skin cells. Using someone else’s cells can cause a serious reaction. Do not let anyone else use your LAVIV. Prior to injection, confirm with your physician that your information on the LAVIV vial is correct. Your healthcare provider will help you to decide whether you are a candidate for LAVIV and may help you avoid some of the adverse reactions from LAVIV. Before getting LAVIV, tell your healthcare provider if you have any medical problems including allergic reactions to any drugs or food, bleeding disorders or take blood-thinning medicines like aspirin, ibuprofen, or COUMADIN® (warfare sodium), keloids or excessive scarring, skin cancer or any malignancy, genetic disorders affecting your skin, immune problems or take medicines that affect your immune system, or any other illness or medical problem. Tell your healthcare provider if you are allergic to the antibiotics amphotericin or gentamicin, bovine materials (products made from cattle), or dimethyl sulfoxide (DMSO). Do not use LAVIV if you have a skin infection on your face because LAVIV treatment can make the infection worse.

The most common side effects of LAVIV are at the injection-site, including redness, bruising, swelling, pain, bleeding, lumps, irritation, and itchiness. In clinical trials with LAVIV, most injection-site adverse reactions resolved within one week and most required no treatment. There are additional adverse reactions that occurred in less than 1% of patients following LAVIV treatment in clinical trials. Talk to your healthcare provider about these adverse reactions. For more information about LAVIV, please see full prescribing information.

For more information about LAVIV, please see the accompanying full Prescribing Information or visit www.mylaviv.com.

Forward-Looking Statements

All statements in this press release that are not based on historical fact are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and the provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. While management has based any forward-looking statements contained herein on its current expectations, the information on which such expectations were based may change. These forward-looking statements rely on a number of assumptions concerning future events and are subject to a number of risks, uncertainties, and other factors, many of which are outside of the Company’s control, that could cause actual results to materially differ from such statements. Such risks, uncertainties, and other factors include, but are not necessarily limited to, those set forth under Item 1A “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2012, as updated in “Item 1A. Risk Factors” in the Company’s Quarterly Reports on Form 10-Q filed since the annual report. The Company operates in a highly competitive and rapidly changing environment, thus new or unforeseen risks may arise. Accordingly, investors should not place any reliance on forward-looking statements as a prediction of actual results. The Company disclaims any intention to, and undertakes no obligation to, update or revise any forward-looking statements. Readers are also urged to carefully review and consider the other various disclosures in the Company’s public filings with the SEC.

Contact:

Media
Marina Maher Communications, LLC
Heather Adamson,
212-485-6806
hadamson@mahercomm.com

or

Investors
Fibrocell Science Desk
Redington, Inc.
212-926-1733
fibrocell@redingtoninc.com
203-222-7399

April 02, 2013, EXTON, PA – Fibrocell Science, Inc. (OTC: FCSC) reported its financial and operating results for the year ended December 31, 2012.

“2012 has been a pivotal year for Fibrocell,” said David Pernock, Fibrocell Chairman and Chief Executive Officer. In 2012, Fibrocell launched, LAVIV^® (azficel-T), an autologous fibroblast cell product indicated for improving the appearance of smile-line wrinkles and the company’s first FDA-approved product. LAVIV has been in the market on a limited basis for the past year and the response from physicians and their patients has been positive. As one of only eight cell-based products approved by the U.S. Food and Drug Administration (FDA), LAVIV is the first and only approved for aesthetic use and is the only one that utilizes the patient’s own fibroblast cells.

Fibrocell is now working to develop a deep and meaningful pipeline of premium, first-in-class products based on its autologous fibroblast technology. To that end, the company has embarked on a collaboration with Intrexon Corporation that will focus on rare genetic collagen deficiencies. The Company also plans to initiate multiple Phase II clinical programs in restrictive burn scars and in vocal cord scars in 2013.

“2012 was clearly a watershed year for Fibrocell. We established the viability of our core fibroblast technology with LAVIV® and are working to unlock its potential in medical and aesthetic areas with significant unmet need,” said Mr. Pernock “Having successfully raised more than $40 million in new capital, we can now pursue additional indications for our autologous fibroblasts in areas with a significant and unmet medical need such as restrictive burn scars, vocal cord scars, and recessive dystrophic epidermolysis bullosa (RDEB). Fibrocell is at and will remain at the leading edge of personalized regenerative medicine. In the coming weeks we intend to provide detail on these activities and others.”

LAVIV^® Highlights

LAVIV continues to receive favorable recognition in national beauty and fashion magazines. It has also received numerous awards for innovation, including recognition in the 12^th Annual Wall Street Journal Technology Innovation Awards program.

Commercially, 2012 was devoted to introductory marketing of LAVIV and to helping leading physicians gain clinical experience using this new technology. The introductory price for LAVIV, which is below our cost of manufacturing, was intended to stimulate usage and clinical experience. Now that the product is established in clinical practice, we will announce a price increase later this month that better reflects its market value.

Financial highlights:

–As of December 31, 2012, cash and cash equivalents were $31.3 million compared to $10.8 million a year ago.

–For the year ended December 31, 2012, Fibrocell posted a net loss of $23.2 million on revenue of $153,000 compared to a net loss of $31.4 million on zero revenue for the year ended December 31, 2011.

–Fibrocell sold greater than $40 million in new equity in October 2012. As a part of the transaction, the company repaid or converted to equity all of its outstanding debt and all preferred shares were converted to common shares. The company currently has no debt.

Product Pipeline Highlights

LAVIV has validated the utility and commercial importance of our core technology. We are now in a position to apply our knowledge of the autologous cell manufacturing processes and regulatory requirements toward the development and commercialization of autologous products for new medical and aesthetic applications where autologous fibroblasts could play a key role. We are particularly focused on indications that present a critical unmet need and offer significant market and reimbursement potential. We will leverage the same core technology and manufacturing process to improve the lives of patients beyond our current aesthetic indication. The following programs demonstrate our work towards broadening the potential of our autologous fibroblast technology platform:

Rare Collagen Deficiencies — Fibrocell has entered into an Exclusive Channel Collaboration (ECC) with Intrexon Corporation to explore the use of genetically modified autologous fibroblasts cells for the treatment of the genetic blistering disorder epidermolysis bullosa (EB), and more specifically, recessive dystrophic epidermolysis bullosa (RDEB), the most severe form of the disease. RDEB is an autosomal recessive disorder characterized by the loss of collagen type VII, an important protein component of the anchoring fibers that connect the dermis to the epidermis.

RDEB typically presents at birth, and affected children experience widespread blistering and areas of missing skin in response to friction or minor injury, such as rubbing, scratching, or abrasions. Severe cases can lead to disfigurement through fusion of the fingers and toes, muscle contractures that restrict movement, corneal inflammation or scarring leading to vision loss, anemia, and other serious medical problems. RDEB has the highest rate of morbidity and mortality amongst the genetic blistering disorders. RDEB patients who survive to adulthood most often succumb to cutaneous squamous cell carcinoma.

Through its collaboration with Intrexon, Fibrocell is uniquely positioned to leverage its proven fibroblast technology with Intrexon’s synthetic biology expertise to modify a patient’s own fibroblasts in order to produce functional collagen VII. A patient’s own gene modified fibroblasts hold the potential to treat this rare genetic condition by partially restoring normal collagen VII production and thus establishing physiological dermal-epidermal junctions. The availability of such a treatment would address a significant unmet clinical need given approximately 7 in 1,000,000 live births in the US, Europe, and Asia are diagnosed with RDEB. Presently there are no FDA-approved products to treat the underlying cause of the disease, and clinicians and patients must rely solely on palliative care to reduce patient suffering.

Restrictive Burns Scars – Approximately 45,000 people in the United States are hospitalized each year with severe burns, leaving many with restrictive burn scars that can cause disfigurement, decreased mobility and continuous pain. We believe that the intrinsic role fibroblasts play in wound healing could be applied to these patients to help improve their range of motion and reduce scar pain. In the second quarter of 2013 we plan to start a Phase II trial of our autologous fibroblast technology for the treatment of restrictive burns scars to assess impact on range of motion, pain and scar appearance. Because there are currently no FDA-approved products to treat restrictive burn scars, commercialization of such a treatment would be a significant breakthrough in the market.

Vocal Cord Scars – Scar tissue on the vocal cords reduces their suppleness and can affect voice tone and loudness; in fact, extreme scarring can leave impacted individuals unable to verbally communicate. Vocal cord scarring can be caused by aging, excessive exertion (such as experienced by singers and public speakers) and is a frequent side effect of cancer radiation therapy and surgical trauma. It impacts an estimated 200,000 to 700,000 people in the United States. Restoration of normal collagen levels may enable vocal cords to regain their lost suppleness. Our pilot clinical study showed that the injection of autologous fibroblasts is safe and appears to produce both objective and subjective improvements in voice quality that were sustained up to 12 months after treatment. In furthering this research, we plan to commence a Phase II study of our autologous fibroblast cell technology for vocal cord scars in the second half of 2013. We will be assessing improvement in voice quality. With voice therapy the most common attempted remedy and no commercially available treatments to date, we believe this could present a lucrative new application for our autologous fibroblast technology.

Acne Scars – Acne is the most common skin disorder in the United States and leaves an estimated 20 million Americans suffering from acne scarring as a result. Following the completion of a successful Phase II study of our autologous fibroblast technology for the treatment of moderate to severe acne scars, which met all efficacy end points and was well tolerated by participants, we entered discussions with the FDA regarding the design of a Phase III program. Presently there are no FDA-approved medical products for the treatment of acne scarring. Given the promising early results, we are eager to further examine the potential value our autologous fibroblast technology could provide in this widespread condition.

Skin-derived Stem Cell Initiatives/UCLA/MIT – We entered into an exclusive license agreement with UCLA to develop methods and techniques for using skin cells for generating stem cells that could serve as versatile tissue progenitors in regenerative medicine applications.

Under our collaborative agreement with MIT, researchers there are working to develop a scalable method to cost-effectively culture and grow the cell types identified by UCLA into relevant quantities.

Fibrocell Science Autologous Crème™ — We initiated a marketing claims study of a new autologous skin care cream for treating mild to severe photo-damaged skin. The cream will leverage the LAVIV manufacturing process, providing the first and only topical product containing personalized growth factors and proteins derived from a person’s own fibroblast cells. We expect to introduce the product in the second half of 2013 under the name Fibrocell Science Autologus Crème™.

About Fibrocell Science, Inc.

Fibrocell Science, Inc. (FCSC) is an autologous cellular therapeutic company focused on the development of innovative products for aesthetic, medical and scientific applications. Fibrocell Science is committed to advancing the scientific, medical and commercial potential of autologous skin and tissue, as well as its innovative cellular processing technology and manufacturing excellence. For additional information, please visit www.fibrocellscience.com.

Forward-Looking Statements

All statements in this press release that are not based on historical fact are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and the provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements include, without limitation, (a) the Company’s ability to build on its core technology and expand its development portfolio to include treatments for restrictive burn scars, vocal cord scars, and rare genetic collagen deficiencies; (b) the Company’s ability, through its collaboration with Intrexon Corporation to leverage its fibroblast technology to provide a potential treatment for RDEB that would enable normal collagen production; (c) the Company’s ability to start a Phase II trial for the treatment of restrictive burns scars in the second quarter of 2013; (d) the Company’s ability to start a Phase II study for vocal cord scars in the second half of 2013; and (e) the Company’s ability to introduce its autologous skin care crème product in the second half of 2013. While management has based any forward-looking statements contained herein on its current expectations, the information on which such expectations were based may change. These forward-looking statements rely on a number of assumptions concerning future events and are subject to a number of risks, uncertainties, and other factors, many of which are outside of the Company’s control, that could cause actual results to materially differ from such statements. Such risks, uncertainties, and other factors include, but are not necessarily limited to, those set forth under Item 1A “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2012, as updated in “Item 1A. Risk Factors” in the Company’s Quarterly Reports on Form 10-Q filed since the annual report. The Company operates in a highly competitive and rapidly changing environment, thus new or unforeseen risks may arise. Accordingly, investors should not place any reliance on forward-looking statements as a prediction of actual results. The Company disclaims any intention to, and undertakes no obligation to, update or revise any forward-looking statements. Readers are also urged to carefully review and consider the other various disclosures in the Company’s public filings with the SEC.

Contact:

Media
Marina Maher Communications, LLC
Heather Adamson,
212-485-6806
hadamson@mahercomm.com

or

Investors
Fibrocell Science Desk
Redington, Inc.
212-926-1733
fibrocell@redingtoninc.com
203-222-7399

“We continue to be pleased with the results of our collaboration with UCLA to pursue the full potential of fibroblasts,” said David Pernock, CEO and Board Chair, Fibrocell Science.

The cells may be used by academic researchers and pharmaceutical companies to evaluate new drug compounds for safety and to develop patient-specific therapies for multiple disease states, including heart disease, Parkinson’s disease and diabetes. Using skin cells is more advantageous to the patient than obtaining cells from bone marrow or adipose tissue (fat). A skin biopsy is quicker to perform, less painful and minimally invasive.

Dr. Byrne’s study found human skin cells cultured in the presence of a chemical known as BAY11 resulted in reproducible increased expression of the OCT4 gene that did not inhibit normal cell growth. OCT4 is involved in many cell processes, but is primarily known to maintain pluripotency and regulate cell differentiation. It is typically used as a marker to identify undifferentiated cells.

The development of a more stable method to create iPS cells from skin cells allows for the potential of a reproducible commercial manufacturing process. The study was performed at the Eli and Edythe Broad Center of Regenerative Medicine & Stem Cell Research and Department of Molecular and Medical Pharmacology at UCLA in conjunction with the Department of Cell Biology and Neuroscience at Rutgers University.

About Fibrocell Science, Inc.

Fibrocell Science, Inc. (FCSC) is an autologous cellular therapeutic company focused on the development of innovative products for aesthetic, medical and scientific applications. Fibrocell Science is committed to advancing the scientific, medical and commercial potential of autologous skin and tissue, as well as its innovative cellular processing technology and manufacturing excellence. For additional information, please visit fibrocellscience.com.

Forward-Looking Statements

All statements in this press release that are not based on historical fact are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 and the provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements include, without limitation, the final discovery of a more predictable, commercially-viable method of producing stable, induced pluripotent stem cells (iPSC) and the ability of the Company to generate any future licensing opportunities based on the foregoing. While management has based any forward-looking statements contained herein on its current expectations, the information on which such expectations were based may change. These forward-looking statements rely on a number of assumptions concerning future events and are subject to a number of risks, uncertainties, and other factors, many of which are outside of the Company’s control, that could cause actual results to materially differ from such statements. Such risks, uncertainties, and other factors include, but are not necessarily limited to, those set forth under Item 1A “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2011, as updated in “Item 1A. Risk Factors” in the Company’s Quarterly Reports on Form 10-Q filed since the annual report. The Company operates in a highly competitive and rapidly changing environment, thus new or unforeseen risks may arise. Accordingly, investors should not place any reliance on forward-looking statements as a prediction of actual results. The Company disclaims any intention to, and undertakes no obligation to, update or revise any forward-looking statements. Readers are also urged to carefully review and consider the other various disclosures in the Company’s public filings with the SEC.

Contact:

Media
Marina Maher Communications, LLC
Heather Adamson,
212-485-6806
hadamson@mahercomm.com

or

Investors
Fibrocell Science Desk
Redington, Inc.
212-926-1733
fibrocell@redingtoninc.com
203-222-7399